Modulating offspring responses: concerted effects of stress and immunogenic challenge in the parental generation

VIDELA, EMILIANO A.; MARÍN, RAÚL H.; VIDELA, EMILIANO A.; MARÍN, RAÚL H.; GIAYETTO, OCTAVIO; JAIME, CRISTIAN; GIAYETTO, OCTAVIO; JAIME, CRISTIAN; CHACANA, PABLO; NAZAR, F. NICOLÁS; CHACANA, PABLO; NAZAR, F. NICOLÁS

JOURNAL OF EXPERIMENTAL BIOLOGY

COMPANY OF BIOLOGISTS LTD

Año: 2020

0022-0949

The perception, processing and response to environmental challenges involves the activation of the immuno-neuroendocrine (INE) interplay. Concerted environmental challenges might induce trade-off when resource allocation to one trait occurs at the expense of another, also producing potential transgenerational effects in the offspring. We evaluated whether concerted challenges, in the form of an immune inoculum against inactivated Salmonella Enteritidis (immune challenge, ICH) and a chronic heat stress (CHS) exposure on adult Japanese quail, modulates the INE responses of the parental generation and their offspring. Adults were inoculated and later exposed to a CHS along 9 consecutive days. The last 5 days of CHS, eggs were collected for incubation. Chicks were identified according to their parental treatments and remained undisturbed. Induced inflammatory response, Heterophil/Lymphocyte (H/L) ratio and specific humoral response against sheep red blood cells (SRBC) were evaluated in both generations. Regardless of the ICH, stressed adults showed a reduced inflammatory response (p