"Leptospiral infection: a serosurvey in urban and rural communities in Olavarría county (Argentina)"

RIVERO, MARIANA; SCIALFA, EXEQUIEL; APPENDINO, HECTOR; BARRAGAN, PAOLA; MARTIN, FELIX; MORON, BETSABE; SILVA, JULIA; BARBERO, MELINA; TISNÉS, ADELA; ESTEIN, SILVIA; SIGNORINI, MARCELO ; GONZALEZ AYALA, SILVIA; BOLPE, JORGE

The Journal of Infection in Developing Countries (JIDC)

Department of Biomedical Sciences, University of Sassari, Sassari, Italy

Lugar: Roma; Año: 2022

1972-2680

Introduction: Leptospirosis is a neglected zoonotic disease, endemic mainly in countries, mostly in vulnerable populations. Methodology: A cross sectional-study was carried out in 557 subjects from Olavarría county (Argentina) with the aim to determine the factors associated to Leptospira sp. seroprevalence. A survey was also carried out to obtain clinical and epidemiological data. Serum was analyzed by Microscopic Agglutination Test (MAT). Chi-square or Fisher Exact tests were used to assess association between the MAT results and the exploratory variables. For the variables statistically associated, odds ratios (ORs) and 95% confidence intervals (95% CI) were calculated. Individuals from Olavarría city were georeferenced to describe the spatial distribution and to search for spatial clusters of seropositive results. Results: The overall prevalence of leptospirosis infection was 7.00%, higher in rural (19.66%) than in urban populations (3.64%) (p