Seroprevalencia de leptospirosis humana en una comunidad rural del partido de Tandil (Argentina). Identificación de factores de riesgo y análisis espacial.

SILVA, JULIA; SCIALFA, EXEQUIEL; TRINGLER, MATIAS; RODRIGUEZ, MARCELO; ADELA TISNÉS; LINARES, SANTIAGO; RIVERO, MARIANA

REVISTA ARGENTINA DE MICROBIOLOGíA

ASOCIACION ARGENTINA MICROBIOLOGIA

Lugar: Buenos Aires; Año: 2022

0325-7541

Leptospirosis is a neglected zoonosis, widely distributed in the world. Although it isendemic in Argentina, prevalence remains unknown. The aims of the study were: i) todetermine the prevalence of leptospirosis in humans from a rural community in Tandilcounty, Argentina, ii) to identify infecting Leptospira spp. serogroups, iii) to identifyfactors associated with the infection, iv) to estimate the population attributable fraction(PAF) of the risk factors and v) to determine spatial patterns of the presentation of thedisease and the risk factors related. Blood samples from 202 participants were collected.A survey was conducted to get clinical and epidemiological data. Serological testingwas performed by microscopic agglutination test (MAT). To evaluate associations,univariate and multivariate methods were applied. Spatial clusters were investigated forseroprevalence and for the risk factors. Antibodies were found in 32.2% of participants(95%CI: 25.8-39.1). The most prevalent serogroup was Hebdomadis followed bySejroe; Icterohaemorrhagiae; Tarassovi and Canicola. Living at lower altitudes (OR:13.04; 95%CI: 2.60?65.32); not having access to water supply network (OR: 2.95;95%CI: 1.30?6.69); living close to flooded streets (OR: 2.94; 95%CI: 1.14?7.69) andpracticing water sports (OR: 3.12; 95%CI: 1.12?8.33) were associated withseropositivity. Factors related with housing characteristics, services and infrastructurehad the higher PAF (from 17% to 81%). A spatial cluster with higher rates of positivityand of the main risk factors was determined. This work brings useful data for specificpreventive measures that should be implemented for the control of the disease.