Evidence of porcine circovirus type 2 and co-infection with ungulate protoparvovirus 1 (porcine parvovirus) in mummies and stillborn piglets in subclinically infected farm

SERENA, MARÍA SOLEDAD; DIBÁRBORA, MARINA; OLIVERA, VALERIA; METZ, GERMÁN ERNESTO; ASPITIA, CAROLINA GABRIELA; PEREDA, ARIEL; ECHEVERRÍA, MARÍA GABRIELA; CAPPUCCIO, JAVIER

Infection, Genetics and Evolution

ELSEVIER SCIENCE BV

Año: 2021 vol. 89

1567-1348

Porcine circovirus type 2 (PCV2) and protoparvovirus 1 (PPV) were detected as single infection (6/131) and (11/131) respectively, or co-infection (6/131) in fetuses and stillborn piglets from normal deliveries in a farmwithout reproductive problems. Twenty in twenty-three positive samples were over 70 days of gestation, which iswhen the fetus becomes immunocompetent, and the presence of a NADL-2 PPV strain suggests fetal immunesystem impairment. Phylogenetic analysis of sequences obtained showed that 8/9 sequences are related to cluster13 and the remaining is grouped into cluster 11 sequences. An increase in variability in ORF2 sequences inArgentina was observed. It is not clear whether the detection of fetuses positive to PPV and PCV2 is of epidemiological importance in a subclinically affected farm. However, the results of this study showed that currentlyused vaccines and vaccine protocols do not fully protect against PPV or PCV2 fetus infectio