HPV PREVALENCE AMONG MEN WHO HAVE SEX WITH MEN (MSM) AND TRANS SEX

GONZALEZ JV; BASILETTI J; PANDO MA; DOS RAMOS FARIAS MS; MARONE R; BALAN I; DOLEZAL C; SQUIQUERA L; CARBALLO-DIÉGUEZ A; AVILA MM; PICCONI A

Montreal

Congreso; 26th International Papillomavirus Conference; 2010

Background: There is a lack of information regarding sexually transmitted infections (STIs) among MSM and Trans (transvestites, transsexuals or transgender) Sex Workers (TSW) from Argentina. The present work is part of a broader study which investigated HIV and other STIs prevalence among MSM and TSW in Argentina. Aim: to estimate HPV prevalence in MSM and TSW from Buenos Aires. Materials and methods: Two populations were included: Group 1 (MSM): 500 men recruited through Respondent Driven Sampling, a methodology designed to access hidden populations, used for the first time in Argentina; 131 of them accepted to take anal self –collected brushing samples for HPV study.   Group 2 (TSW): 144 trans recruited by a NGO in streets and among people related to the organization; 120 of them accepted to take anal self –collected brushing samples for HPV study.   HPV detection and genotyping was performed by PCR-Reverse Line Blotting, using GP5+,6+ primers. Results:  Group 1: 131 samples from MSM were analyzed. HPV was detected in 83.2%, corresponding 63.3% to High Risk-HPVs (HR-HPV). Coinfections reached 54.1%, identifying up to 8 different types.  HPV 16 was the most common type (18.3%) followed by HPV 11 and 42 (16.5%); HPV6 (15.6%); HPV66 (11.9%); HPV70 and 45 (11.0%), and HPV18 (10.1 (raw data).  Group 2: 115 samples from Trans were analyzed.  HPV was detected in 97.4%, corresponding 75.0% to HR-HPV.  Coinfections reached 64.3%, identifying up to 10 different types. HPV 16 was the most common type (27.7%) followed by HPV 42 and 81 (16.1%); HPV 58 (15.2%); HPV 51 (12.5%); HPV 18, 39, 6, 43 and 66 (11.6%), and HPV 31, 56 y 11 (9.8%).  Conclusions: The high HPV prevalence observed showed the great vulnerability these populations have, even higher among TSW, setting out the urgent need for preventive interventions and facilitation of the access to health programs