MIXED-METHODS EVALUATION OF A MULTI-COMPONENT MHEALTH INTERVENTION FOR TRIAGE AFTER HPV SELF-COLLECTION: THE ATICA STUDY PROTOCOL

ARROSSI S; PAOLINO M; ORELLANA L; THOUYARET L; KOHLER, RACQUEL E.; VISWANATH, KASISOMAYAJULA

Congreso; 32nd International Papillomavirus Conference; 2018

BACKGROUND Highadherence to triage by HPV+ women with self-collected tests is challenging. TheATICA study (Application of Communication and Information Technologies toSelf-Collection, for its initials in Spanish) will evaluate the effectiveness ofa multi-component mHealth intervention aimed at increasing triage adherenceamong HPV+ women with self-collected tests, compared to usual care. The projectis funded through an R01 grant awarded by NCI/NIH. MethodsATICAstudy is an effectiveness-implementation hybrid type I trial that uses a mixedmethods approach.  A cluster-randomizedtrial design including 200 community health workers (CHWs) will evaluate whetherthe mHealth intervention increases adherence to cytology triage within 120 daysafter testing positive. The intervention will consist of mobile phone text messages(SMS) sent to HPV+ women informing them that the test result is ready forcollection and advising them to go to the health center. An email/SMS messagewill be sent to CHWs to promote contacting women who did not adhere to triage within60 days after testing positive. We will use the Consolidated Framework forImplementation Research (CFIR) and the Reach, Effectiveness, Adoption,Implementation and Maintenance (RE-AIM) frameworks to evaluate implementation ofthe intervention. RESULTS:Planning of field work and randomization of CHWs was carried out throughcollaborative work with Jujuy health authorities. Formative research wascarried out to design content of SMSs and the automatic messaging system. Fieldwork will begin in July 2018.CONCLUSIONS:Findings from the ATICA project will be highly applicable to programs that useor are planning to incorporate HPV self-collection.