INVESTIGADORES
ARIEL Federico Damian
artículos
Título:
Functional classification of plant long noncoding RNAs: a transcript is known by the company it keeps
Autor/es:
LUCERO, LEANDRO; FERRERO, LUC√ćA; FONOUNI-FARDE, CAMILLE; ARIEL, FEDERICO
Revista:
NEW PHYTOLOGIST
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2020
ISSN:
0028-646X
Resumen:
The extraordinary maturation in high-throughput sequencing technologies has revealed the existence of a complex network of transcripts in eukaryotic organisms, including thousands of long noncoding (lnc) RNAs with little or no protein-coding capacity. Subsequent discoveries have shown that lncRNAs participate in a wide range of molecular processes, controlling gene expression and protein activity though direct interactions with proteins, DNA, or other RNA molecules. While significant advances have been achieved in the understanding of lncRNA biology in the animal kingdom, the functional characterization of plant lncRNAs is still in its infancy and remains a major challenge. In this review, we report emerging functional and mechanistic paradigms of plant lncRNAs and partner molecules and discuss how cutting-edge technologies may help to identify and classify yet uncharacterized transcripts into functional groups.