POPULATION-BASED STUDY OF METABOLIC SYNDROME IN OLDER ADULTS

REPOSSI G; PRIOTTO S; BAROTTO NN; ASTORQUIZA P; BARBOSA MC; LÓPEZ PM; FARÍAS S; DIAZ-GEREVINI GT

Paris

Congreso; World Congress of Controversies in Obesity and Diabetes 2023; 2023

Controversies in Obesity and Diabetes Group

Metabolic syndrome (MS) is a set of metabolic alterations considered a riskfactor for developing cardiovascular disease and diabetes. In recent years, dueto harmful changes in lifestyle, the increase in the prevalence of SM worldwideis alarming. In Argentina, epidemiological studies on SM report a prevalence of25%. One of the groups at highest risk for this syndrome are olderadults. Objectives: Determine the prevalence of MS and its diagnosticcomponents. To analyze whether MS is associated with an increase in mortality.A retrospective observational study was carried out (period 2018-2022) of allmedical records (n=1020) of older adults (≥65 years), patients at the SanRicardo Pampuri Primary Care Medical Center in the central area of Argentina.Diagnostic criteria for MS, present at least 3 of these 5 components:1-BMI ≥30 and/or waist circumference greater than or equal to 94 cm in menand 88 cm in women;2-Triglycerides ≥150 mg/dL;3-HDL cholesterol ≤40 mg/dL in men or ≤50 mg/dL in women and/or totalcholesterol ≥ 200 mg/dL;4-Elevated blood pressure ≥140/90 mmHg;5- Fasting glucose ≥100 mg/dL.These variables were analyzed and the prevalence of MS was determined.Mortality and its causes were studied and the risk for patients with MS wascalculated. Statistical analysis was performed with Infostat (p≤0.05), ANOVA(Tukey post hoc) tests were used for continuous variables and Chi square fordiscrete variables. In this work, the rules of confidentiality and anonymity ofthe participants were respected.Population data: 62% female/38% male. Average age: 78.8.Prevalence: MS=57% (Male: 56% and Women: 59%); obesity=69%,hypertriglyceridemia=57%, hypercholesterolemia=49%, arterialhypertension=69%, hyperglycemia=54%.Mortality: 11.27% in the period. Increased risk of mortality for people with MS(Male=1.26; Female=1.45; OR:1.13). Women with MS have shorter survival (ageof death MS: 77.72 vs. Non-MS: 83.88 years). Qualitative and quantitativedifferences were found in the proportional causes of mortality between thegroup with MS and those without.Conclusion: MS showed a high prevalence in older adults, equally for all components of its diagnosis. MS increased the risk of mortality and decreased survival, more markedly in women. The diagnosis of MS is important, mainly invulnerable populations, to improve its prevention and treatment.