A scientific note on the first report of honeybee venom inhibiting Paenibacillus larvae growth

FERNANDEZ NJ; PORRINI MARTÍN P; PODAZA ENRIQUE; DAMIANI NATALIA; GENDE L; EGUARAS M.J.

APIDOLOGIE

EDP SCIENCES S A

Lugar: Paris; Año: 2014 vol. 45 p. 719 - 721

0044-8435

Honeybee venom (BV) has been recently reported as an important source of antimicrobial peptides. Despite these broad spectrum antimicrobial effects, information about BV effects on infectious pathogens of honeybees is previously absent from the literature. It is a preliminary approach about an alternative natural substance for American Foulbrood control. Results showed that very low concentrations of BV are required to inhibit Paenibacillus larvae vegetative cells growth. The minimal inhibitory concentration values ranged from 3.12 to 8.33 µg/mL, and minimal bactericidal concentration values of 4.16 to 10.42 μg/mL. This paper is the first report on BV antimicrobial activity against P. larvae with no lethal or behavioral effects on bees.