EFFECTS OF AFLATOXIN B1 AND MONENSIN INTERACTION ON LIVER PATHOLOGY AND GUT MORPHOLOGY IN POULTRY. INFLUENCE OF A BIOLOGICAL ADDITIVE

ALEJANDRA MAGNOLI,; VALERIA LORENA POLONI; ANDREA CRISTOFOLINI

Rio de Janeiro

Encuentro; 17 ° ENCONTRO NACIONAL DE MICOTOXINAS; 2021

The aim of this study was to evaluate the effects of AFB1 and MON interaction on liver pathology and gut morphology in poultry, and the influence of the yeast. One-day-old commercial line (Ross 308) poultry (n = 120) were individually weighed and randomly assigned to 8 treatments (15 poultry/treatment, 5 poultry per cage and 3 replicates/treatment). The experimental diets were: group 1: basal diet (BD); group 2: BD + MON (50 mg/kg); group 3: BD + P. kudriavzevii (1 g/kg); group 4: BD + AFB1 (100 μg/kg); group 5: BD + MON + P. kudriavzevii; group 6: BD + AFB1 + P. kudriavzevii; group 7: BD + AFB1 + MON + P. kudriavzevii; group 8: BD + AFB1 + MON. When MON was added, the typical AFB1 macroscopic and microscopic alterations were intensified, in the presence of P. kudriavzevii and MON the toxic effect of AFB1 on liver was not prevented. The smallest apparent absorption area was obtained when AFB1 and MON were added in the feed (p < 0.05). AFB1 and MON interaction demonstrated important toxic effects; although P. kudriavzevii was effective in ameliorating the adverse effects of AFB1 alone on liver pathology and on gut morphology, it was not able to diminish the toxic effects of AFB1 in presence of MON. It suggests that P. kudriavzevii could be used as feed additive or counteracting the toxic effects of AFB1 in poultry production in the absence of MON