Protocol for the validation of LIBS as an analytical method

J. VOROBIOFF; C. RINALDI; N. BOGGIO

Bari

Conferencia; XII world conference on Laser Induced Breakdown Spectroscopy; 2022

CNR NANOTEC - LIBS community

The validation of analytical methods and equipment calibration is a very importantaspect to ensure quality in a chemistry laboratory. Any method that is introduced in alaboratory must be properly documented, and all analysts using that new methodologymust receive adequate training and demonstrate their competency in the new methodbefore beginning to use it in any analysis. New analytical methods, like Laser InducedBreakdown Spectroscopy (LIBS), also need revalidation or at least verification. If amethod is modified or applied to a new situation (e.g., a different sample matrix),revalidation or verification would be required depending on the extent of the modificationand the nature of the new situation. In this work, a set of protocols for the analysis byLIBS of different samples are presented. These cases can be taken as examples to developmore complex systems to prepare guidance for the validation of analytical methodologyand calibration of LIBS equipment used in analytical chemistry. The LIBS communityshould provide support to laboratories in introducing and implementing a qualitymanagement system to include LIBS as a common standard analytical method.