IMTIB   27019
INSTITUTO DE MEDICINA TRASLACIONAL E INGENIERIA BIOMEDICA
Unidad Ejecutora - UE
artículos
Título:
Microbiome Translation Research (InTraMic): An Area of Common and Growing Interest at IMTIB, Hospital Italiano and Instituto Universitario
Autor/es:
GADANO, ADRIAN; LLESUY, SUSANA; BURGOS, VALERIA; BASQUEIRA, ANA; JAUK, FEDERICO; VACCARO, CARLOS A; RISK, MARCELO; PIÑERO, TAMARA; MAZZINI, FLAVIA; BOLONTRADE, MARCELA F.; ARGUERO, JULIETA; PAVICIC, WALTER; FIGARI, MARCELO; TRINKS, JULIETA; ALBERBIDE, JORGE; GIMÉNEZ, MARISA
Revista:
Revista del Hospital Italiano de Buenos Aires
Editorial:
Instituto Universitario Hospital Italiano de Buenos Aires
Referencias:
Lugar: Buenos Aires; Año: 2020 vol. 40 p. 177 - 184
ISSN:
2314-3312
Resumen:
The characterization of the gut microbiome (MBI) in different health states is a line of research in exponential growth given its potential impact on the prevention and treatment of highly prevalent diseases. The technologies available in the 21st century allow for a much more accurate and informative analysis than in the era where studies were based on crops. Characterization is currently based on multi-omic techniques (metagenomics, transcriptomics, metabolomics) that demand a multidisciplinary approach with specialists in molecular biology, bioinformatics and molecular epidemiological. Translational research in microbiome initiative (InTraMic) is one of the lines that undergoes at the Institute of Translational Medicine and Biomedical Engineering (IMTIB). This line began in 2018 with a collaboration with the University of Leeds (United Kingdom) as part of an international pilot study on colorectal cancer. In 2019, with the support of the Novartis Scholarship Next Generation Scientist Program, studies on nonalcoholic fatty liver disease began. That same year an institutional project was presented to the call for projects (PUE 2019) of the National Agency for Scientific and Technological Promotion (ANPCyT), in which the line of bone marrow transplantation was incorporated. Within the framework of The InTraMic, regular meetings are held open to all health personnel where knowledge is exchanged, and new proposals are evaluated. This article provides an update on microbiome taxonomic characterization and describes ongoing lines of research.