PERSONAL DE APOYO
KARAYEKOV Elizabeth Irene
artículos
Título:
A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation
Autor/es:
ACHKAR, NATALIA P.; CHO, SEOK KEUN; POULSEN, CHRISTIAN; ARCE, AGUSTIN L.; RE, DELFINA A.; GIUDICATTI, AXEL J.; KARAYEKOV, ELIZABETH; RYU, MOON YOUNG; CHOI, SUK WON; HARHOLT, JESPER; CASAL, JORGE J.; YANG, SEONG WOOK; MANAVELLA, PABLO A.
Revista:
DEVELOPMENTAL CELL
Editorial:
CELL PRESS
Referencias:
Año: 2018 vol. 46 p. 236 - 247
ISSN:
1534-5807
Resumen:
Achkar et al. show that a nuclear reserve pool of inactive phosphorylated HYL1, an essential cofactor for microRNA biogenesis, is resistant to dark- or shade-induced degradation. Upon light restoration, this HYL1 pool is quickly dephosphorylated to rapidly restore miRNA production and switch the developmental program to light-dependent growth.
