IQAL 26184
INSTITUTO DE QUIMICA APLICADA DEL LITORAL
Unidad Ejecutora - UE
artículos
Título:
Nitropyrroles, Diels-Alder reactions assisted by microwave irradiation and solvent effect. An experimental and theoretical study
Autor/es:
KNEETEMAN, MARÍA N.; DOMINGO, LUIS R.; MANCINI, PEDRO M. E.; ORMACHEA, CARLA M.; CAINELLI, MAURO
Revista:
JOURNAL OF MOLECULAR STRUCTURE
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2017 vol. 1147 p. 155 - 160
ISSN:
0022-2860
Resumen:
The behaviors of N-tosylnitropyrroles acting as electrophilic dienophiles in polar Diels-Alder reactions joint to different dienes of increeased nucleophilicity are analysed. The reactions were developed under microwave irradiation using toluene or protic ionic liquids (PILs) as solvents and in free solvent conditions. In all the cases explored we observed good yields in short reaction times. For these reactions, the free solvent condition and the use of protic ionic liquids as solvents offer similar results. However, the free solvent conditions favor environmental sustainability. The role of PILs in these polar Diels-Alder reactions has been theoretically studied within the Molecular Electron Density Theory.
