INVESTIGADORES
DANTOLA Maria Laura
artículos
Título:
Visible-light photochemistry of 6-formyl-7,8-dihydropterin in aqueous solution
Autor/es:
M. LAURA DÁNTOLA; ANDRÉS H. THOMAS; CAROLINA LORENTE; ESTHER OLIVEROS
Revista:
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
Editorial:
ELSEVIER SCIENCE SA
Referencias:
Lugar: -; Año: 2010 vol. 209 p. 104 - 110
ISSN:
1010-6030
Resumen:
Pterins are a family of
heterocyclic compounds present in a wide range of living systems and are involved
in different photobiological processes. 6-Formyl-7,8-dihydropterin (H2Fop), is a
product of oxidation of several natural occurring pterin derivatives, and its
absorption spectrum presents as special feature an intense band in the visible
region. Studies of the photochemistry of H2Fop in aqueous solutions
under visible radiation and room temperature were performed. The photochemical
reactions were followed by UV-VIS spectrophotometry, electrochemical measurement of dissolved O2, enzymatic methods
for H2O2 determination and HPLC. When H2Fop in air-equilibrated
solution was exposed to light, O2 was consumed, the reactant was
oxidized to 6-formylpterin (Fop), and H2O2 released. When the photolysis took place in the absence of O2, a red compound
was generated. This product was rapidly oxidized to Fop on admission of O2.
The quantum yields of H2Fop
disappearance and of photoproducts formation are reported and the effect of pH
is analyzed. The potential biological implications of the results obtained are
also discussed.