INVESTIGADORES
MARTINEZ Nora Alicia
artículos
Título:
TPRV-1 expression in human preeclamptic placenta
Autor/es:
MARTÍNEZ NORA; CYNTIA E. ABAN; GUSTAVO F. LEGUIZAMÓN; ALICIA E. DAMIANO; MARIANA G. FARINA
Revista:
PLACENTA
Editorial:
W B SAUNDERS CO LTD
Referencias:
Lugar: Londres; Año: 2016 vol. 40 p. 25 - 28
ISSN:
0143-4004
Resumen:
Preeclampsia is a multisystem disorder unique to human pregnancy, characterized by abnormal placentation. Although its causes remain unclear, it is known that the expression of several transporters is altered. Transient receptor potential vanilloid 1 (TRPV-1) is a nonselective cation channel, present in human placenta. Here, we evaluated the expression of TRPV-1 in preeclamptic placentas. We observed a deregulation in TRPV-1 expression in these placentas which may explain the impaired Ca2þ homeostasis found in preeclampsia.
