INVESTIGADORES
MORAN BARRIO Jorgelina
congresos y reuniones científicas
Título:
Characterization of a novel plasmid-borne genetic platform driving blaOXA-58 and aphA6 dissemination in Acinetobacter baumannii clinical strains of Argentina
Autor/es:
CAMERANESI MM; MORAN BARRIO J; LIMANSKY AS; REPIZO G; SALCEDO S; VIALE AM
Lugar:
Atenas
Reunión:
Congreso; 10th International Symposium on the Biology of Acinetobacter; 2015
Resumen:
The emergency of carbapenem-resistant Acinetobacter baumannii constitutes a worrisome problem worldwide. Aminoglycoside therapy is generally employed to treat carbapenem-resistant strains, but the rapid selection of resistant strains rapidly follows antibiotic therapy. Short Re27-like sequences are implicated in site specific recombination processes promoting plasmid evolution, and have been associated to structures carrying OXA-58-like CHDL genes. We studied here the molecular causes of combined carbapenem- and aminoglycoside-resistances and their possible dissemination mechanisms among A. baumannii clinical strains isolated in clinical institutions of Argentina.
