Clues on syntenic relationship among some species of Oryzomyini and Akodontini Tribes (Rodentia: Sigmodontinae)

SUÁREZ PABLO; CLEUSA YOSHIKO NAGAMACHI; CECILIA LANZONE; MATIAS MAXIMILIANO MALLERET; PATRICIA CAROLINE MARY O?BRIEN; MALCOLM ANDREW FERGUSON-SMITH; JULIO CESAR PIECZARKA

PLOS ONE

PUBLIC LIBRARY SCIENCE

Lugar: San Francisco; Año: 2015

1932-6203

Sigmodontinae rodentsrepresent one of the most diverse and complex components of the mammalian faunaof South America. Among them most species belongs to Oryzomyini and Akodontinitribes. The highly specific diversification observed in both tribes ischaracterized by a high variability of diploid complements, which varies from 2n=10 to 86. Given this diversity,a consistent hypothesis about the origin and evolution of chromosomes directlydepends on the correct establishment of synteny analyzed in a suitablephylogenetic framework. The chromosome painting technique has been particularlyuseful to identify chromosomal synteny regardless of the magnitude ofchromosome differences. In order to extend our knowledge of the homeologicalrelationships established between Akodontini and Oryzomyini species, we analyzedthe species Akodon montensis (2n=24) and Thaptomys nigrita (2n=52) both from the tribe Akodontini, with chromosomeprobes of Hylaeamys megacephalus (2n=54) of the tribeOryzomyini. The results showed that at least 12 of the 26 autosomal chromosomepairs of H. megacephalus shown conserved synteny in A. montensis and 14 in T. nigrita.Akodon montensis, as well as some species of the Akodon cursor speciesgroup, has a highly fused karyotype, therefore, many syntenic associationsobserved probably represent synapomorphies of these species group. However, aset of such associations of H. megacephalus chromosome probes (6/21;3/25; 11/16/17; and, 14/19) provides phylogenetic information for both tribes.An extension of these observations to other members of Akodontini and Oryzomyinitribes becomes imperative to improve our knowledge about chromosome evolutionin both these groups.