4D Flow MRI Quantification of Flow Disorganization in Aging and Aortic Dilation

GILLES SOULAT; DAMIAN CRAIEM; ELIE MOUSSEAUX; ARIEL PASCANER; THOMAS DIETENBECK; YASMINA CHENOUNE; SOPHIA HOURIEZ--GOMBAUD-SAINTONGE; UMIT GENCER; EMILIE BOLLACHE; NADJIA KACHENOURA

Nantes

Congreso; 31st annual SMRA meeting; 2019

PURPOSE: Referral to surgery in thoracic aortic aneurysms (TAA) is based on maximal diameters (Dmax) measured from imaging, which are known to have a high diagnosis failure rate [1]. In addition to geometry, 4D flow MRI [2] provides a comprehensive flow imaging. Thus, our aim was to evaluate the ability of 4D flow MRI quantitative flow indices to characterize TAA.RESULTS: While AA Dmax varied by 1.4 folds between TAV and OC, VBF varied by 6.5 folds and Ecc and Angle varied by 1.3 to 1.7 folds between the two groups (Figure 2). Moreover, VBF varied by 12.7 folds between the aneurismal AA as compared to descending aorta (DA). Finally VBF varied consistently with age and was able to detect AA dilation with an accuracy of 0.98, while Ecc and Angle had an accuracy of 0.78 and 0.89, respectively (Figure 3).DISCUSSION: 4D flow MRI was used to provide an insight into quantitative flow indices and their ability to characterize aortic alterations with aging and disease. Variation of such flow indices, specifically backward flow in aneurysmal aorta is substantially higher than variations in diameters. Their added clinical value to rupture or dissectionprediction needs to be demonstrated in larger longitudinal studies.