INVESTIGADORES
FACCHINETTI Maria Marta
artículos
Título:
Synthesis and Biological Evaluation of a New Vitamin D2 Analogue
Autor/es:
GÁNDARA ZOILA; PÉREZ MANUEL ; SALOMÓN DÉBORA G. ; FERRONATO MARÍA J. ; FERMENTO MARÍA E. ; CURINO ALEJANDRO C; FACCHINETTI MARÍA M.; GÓMEZ GENEROSA; FALL YAGAMARE
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 2012 vol. 22 p. 6276 - 6279
ISSN:
0960-894X
Resumen:
A new vitamin D2 analogue was synthesized using the Julia-Kocienski olefination. It has antiproliferative effects on cell lines from squamous cell carcinomas of colon and head and neck, but is also as hypercalcaemic as calcitriol in vivo
