INVESTIGADORES
DUS SANTOS Maria Jose
artículos
Título:
Chicken egg yolk antibodies against bovine respiratory syncytial virus neutralize the virus in vitro
Autor/es:
FERELLA ALEJANDRA; BELLIDO D; CHACANA PABLO; ANDRES WIGDOROVITZ; DUS SANTOS MARIA JOSE; MARINA VALERIA MOZGOVOJ
Revista:
PROCEDIA IN VACCINOLOGY
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Año: 2012 vol. 6 p. 33 - 38
ISSN:
1877-282X
Resumen:
Bovine respiratory syncytial virus (BRSV) and its counterpart in humans (HRSV) are two closely related virus, which are the leading cause of severe respiratory syndrome in calves and young children, respectively. Passive immunization can be a practical alternative to conventional vaccination in order to prevent the disease. In this report the production of chicken egg yolk IgY and its ability to neutralize BRSV in vitro were assessed. Purified IgY against BRSV specifically recognized BRSV in a dot blot assay and was able to neutralize the virus in a viral neutralization assay. These results demonstrate the potential use of IgY as a prophylactic treatment against RSV infection
