INVESTIGADORES
DI CHENNA Pablo Hector
artículos
Título:
Rearrangement of 4Ò,5Ò-methylenepregnanes: a simple approach to A-homopregnanes and 5Ò-methylpregnanes.
Autor/es:
DI CHENNA PABLO H.; DANSEY, M.V.; GHINI, ALBERTO A.; BURTON, GERARDO
Revista:
Arkivoc
Editorial:
ARKAT USA
Referencias:
Año: 2005 vol. xii p. 154 - 162
ISSN:
1551-7004
Resumen:
Abstract
A-homopregnanes and 5β-methylpregnanes were prepared from the easily available 3β-hydroxy-20β-acetoxy-4β,5β-methylenepregnane by cationic and radical rearrangements respectively. The A-homopregnane was formed in a single step upon spontaneous rearrangement and elimination by treatment of the cyclopropyl alcohol with BF3.Et2O. The 5β-methylpregnane was obtained by cleavage of the hydrazone of the corresponding cyclopropylketone followed by rearrangement mediated by mercury(II) hydrides
