INVESTIGADORES
ABBA Martin Carlos
artículos
Título:
RHBDD2: a 5-fluorouracil responsive gene overexpressed in the advanced stages of colorectal cancer
Autor/es:
LACUNZA E; CANZONERI R; RABASSA; ZWENGER A; SEGAL-EIRAS A; CROCE MV; ABBA MC
Revista:
TUMOR BIOLOGY
Editorial:
KARGER
Referencias:
Año: 2012 vol. 33 p. 2393 - 2399
ISSN:
1010-4283
Resumen:
In previous studies, we identified rhomboid domain containing 2 (RHBDD2) gene to be markedly overexpressed in breast cancer patients that developed recurrence of the disease. In this study, we evaluated for the first time RHBDD2 gene expression in colorectal cancer (CRC). Five public available DNA microarray studies were compiled in a homogeneous dataset of 906 colorectal samples. The statistical analysis of these data showed a significant increase of RHBDD2 expression in the advanced stages of CRC (p
