The intestinal mucosa as a reservoir of Human Immunodeficiency virus type 1-infection after

BELMONTE L; OLMOS M; FANIN A; PARODI C; BARÉ P; CONCETTI H; PÉREZ H; DE BRACCO MM; CAHN P

AIDS - AN INTERNATIONAL MONTHLY JOURNAL

Lippincott Williams & Wilkins

Año: 2007 vol. 21 p. 2106 - 2108

0269-9370

The presence of HIV-1 RNA in distal duodenal mucosa was evaluated in 44 HIV-1 positive patients. HIV-1 RNA was detected in gut tissue in antiretroviral (ARV) naive patients with high plasma viral load (pVL), as well as in patients on HAART with pVL below the limit of detection and in patients on HAART with virological failure. Therefore, the intestinal mucosa seems to serve as a reservoir poorly influenced by levels of pVL or HAART.