INVESTIGADORES
GIACOMODONATO Monica Nancy
artículos
Título:
Host response to a dam mutant of Salmonella enterica serovar enteritidis with a temperature-sensitive phenotype.
Autor/es:
GIACOMODONATO MN, SARNACKI SH, CACCURI RL, SORDELLI DO, CERQUETTI MC.
Revista:
INFECTION AND IMMUNITY
Editorial:
Americam Society for Microbiology
Referencias:
Lugar: Washington; Año: 2004 vol. 72 p. 5498 - 5501
ISSN:
0019-9567
Resumen:
The temperature-sensitive dam mutant strain of Salmonella enterica serovar Enteritidis SD1 is highly attenuated and induces innate and protective immunity in mice. SD1 activates NF-êB and induces gamma interferon secretion. Early interaction of the SD1 mutant with intestinal epithelial cells was associated with ruffling of enterocytes. Invading bacteria were found inside Peyer?s patches after inoculation.
