INVESTIGADORES
MONTEOLIVA Mariela Ines
congresos y reuniones científicas
Título:
Contribution of proline dehydrogenase to hypersensitive cell death and disease resistance in Arabidopsis
Autor/es:
ALVAREZ, ME; MONTEOLIVA, MI; CECCHINI NM; HAJIREZAEI, M-R
Lugar:
Limassol
Reunión:
Congreso; Plant Abiotic Stress: From Systems Biology to Sustainable Agriculture; 2011
Institución organizadora:
Cost Action FA0605
Resumen:
L-proline (Pro) is converted into delta 1-pyrroline-5-carboxylate (P5C) by Pro dehydrogenase (ProDH). P5C is usually transformed into glutamate (Glu) by P5C dehydrogenase (P5CDH). However, under particular conditions, P5C is reduced back to Pro by P5C reductase (P5CR) activating the Pro/P5C cycle together with ProDH. Our results confirmed that Pro catabolism is activated in HR before the onset of cell death and that P5CDH and P5CR display different activities along HR progression to activate the Pro/P5C cycle. We speculate that the Pro/P5C cycle potentiates hypersensitive cell death through ROS accumulation.
