Premenopausal Women May Not Be Protected Against Early Vascular Disease In The Presence Of Diabetes

GARCÍA NESTOR H; HERNAN A PEREZ; J. DAVID SPENCE; LUIS J. ARMANDO

New Orleans

Congreso; 2013 HBPR Council of High Blood Pressure; 2013

American heart Association

Coronary heart disease (CHD) is the leading cause of death among women. Currently, global risk assessment derived by a Framingham risk equation is used to identify women at increased risk, but still we do not detect them early enough to decrease the rate of cardiovascular events. Perhaps we overestimate their protection during the premenopausal and early postmenopausal years, and overestimate the sensitivity of risk scores. Methods: A descriptive cross-sectional study in primary prevention in 1256 women (age 19-84) from Argentina. FRS with body mass index (FRSbmi) and PTP-TPA were used for the evaluation. TPA by ultrasound was determined as previously described by Spence et al (Stroke 2002;33;2916-2922). Patients were divided into DMII (n=293) and control groups (n=963) and then each group was divided according to age,