INVESTIGADORES
JORAY Mariana Belen
congresos y reuniones científicas
Título:
Synergistic effect of the antibacterial compound 23-methyl-6-O-desmethylauricepyrone isolated from Achyrocline satureioides.
Autor/es:
JORAY, M.B.; PALACIOS, S. M.; CARPINELLA, M.C.
Lugar:
Córdoba
Reunión:
Congreso; "1° REUNIÓN INTERNACIONAL DE CIENCIAS FARMACEUTICAS"; 2010
Institución organizadora:
Facultad de Ciencias Bioquímicas y Farmacéuticas UNR
Resumen:
Staphylococcus aureus causes a wide range of infectious diseases in humans (1) from relatively mild skin infections such as folliculitis and furunculosis to life-threatening conditions, including sepsis, deep abscesses, pneumonia, osteomyelitis, and infective endocarditis (2). As a result of a study of the antibacterial activity of Achyrocline satureioides a bioactive compound was identified. A remarkable inhibitory effect of this compound on the mentioned pathogenic bacterium was determined. Then, the antibacterial activity of combinations of this active principle with subinhibitory concentrations of commercial antibiotics was investigated.
