INVESTIGADORES
LUQUE Guillermina Leticia
artículos
Título:
Characterization of carbon paste electrodes modified with manganese based perovskites-type oxides from the amperometric determination of hydrogen peroxide
Autor/es:
GUILLERMINA L. LUQUE, NANCY F. FERREYRA, A. GABRIELA LEYVA, GUSTAVO A. RIVAS
Revista:
SENSORS AND ACTUATORS B-CHEMICAL
Editorial:
Elsevier
Referencias:
Año: 2009 vol. 142 p. 331 - 336
ISSN:
0925-4005
Resumen:
This work proposes the amperometric determination of hydrogen peroxide reduction and oxidation as
a tool for the characterization of La1−xAxMnO3 perovskites dispersed in a graphite composite electrode
(carbon paste electrode, CPE). The catalytic activity of perovskites towards the oxidation and reduction of
hydrogen peroxide is highly dependent on the nature of the A cation and on the temperature and time of
calcination employed during the synthesis. Therefore, the selection of the optimal synthesis conditions
to obtain the best catalytic activity towards hydrogen peroxide can be performed from amperometric
determinations.
We also report the analytical application of the perovskite modified CPE through the quantification
of hydrogen peroxide in two real samples. Some preliminary results about the usefulness of
La0.66Sr0.33MnO3CPE to develop a glucose biosensor by incorporation of the enzyme glucose oxidase
(GOx) within the electrode are also reported. The difference in sensitivity to glucose at CPEGOx and
CPELa0.66Sr0.33MnO3GOx (11.9uAmol−1 L and 158.1uAmol−1 L, respectively), clearly demonstrate the
advantages of the association of the biocatalytic activity of GOx and the catalytic activity of perovskites
towards hydrogen peroxide oxidation/reduction, and opens the doors to the development of new sensors
for other important bioanalytes.1−xAxMnO3 perovskites dispersed in a graphite composite electrode
(carbon paste electrode, CPE). The catalytic activity of perovskites towards the oxidation and reduction of
hydrogen peroxide is highly dependent on the nature of the A cation and on the temperature and time of
calcination employed during the synthesis. Therefore, the selection of the optimal synthesis conditions
to obtain the best catalytic activity towards hydrogen peroxide can be performed from amperometric
determinations.
We also report the analytical application of the perovskite modified CPE through the quantification
of hydrogen peroxide in two real samples. Some preliminary results about the usefulness of
La0.66Sr0.33MnO3CPE to develop a glucose biosensor by incorporation of the enzyme glucose oxidase
(GOx) within the electrode are also reported. The difference in sensitivity to glucose at CPEGOx and
CPELa0.66Sr0.33MnO3GOx (11.9uAmol−1 L and 158.1uAmol−1 L, respectively), clearly demonstrate the
advantages of the association of the biocatalytic activity of GOx and the catalytic activity of perovskites
towards hydrogen peroxide oxidation/reduction, and opens the doors to the development of new sensors
for other important bioanalytes.0.66Sr0.33MnO3CPE to develop a glucose biosensor by incorporation of the enzyme glucose oxidase
(GOx) within the electrode are also reported. The difference in sensitivity to glucose at CPEGOx and
CPELa0.66Sr0.33MnO3GOx (11.9uAmol−1 L and 158.1uAmol−1 L, respectively), clearly demonstrate the
advantages of the association of the biocatalytic activity of GOx and the catalytic activity of perovskites
towards hydrogen peroxide oxidation/reduction, and opens the doors to the development of new sensors
for other important bioanalytes.0.66Sr0.33MnO3GOx (11.9uAmol−1 L and 158.1uAmol−1 L, respectively), clearly demonstrate the
advantages of the association of the biocatalytic activity of GOx and the catalytic activity of perovskites
towards hydrogen peroxide oxidation/reduction, and opens the doors to the development of new sensors
for other important bioanalytes.