Effect of MWCNT as SPE packing material for the separation of chiral emerging contaminants.

VERONICA M. LANARO; CECILIA M. PERALTA; LORENA L. SOMBRA; PATRICIA W. STEGE

Cordobá

Congreso; 3º Reunión Internacional de Ciencias Farmacéuticas.; 2014

Nowadays the emerging pollutants have a great concern, and between them the most studied are pharmaceutical drugs. These chiral compound often exhibit different effects in pharmacological activity, transport mechanism, metabolism pathway and toxicity. Specifically, β-blockers are sold and administered as a racemic mixture, but the (S) enantiomer is pharmacologically active one. Paradoxically, the (R) enantiomer is the one which has negative and toxic effects. Carboxylated multiwalled carbon nanotubes (cMWCNT) have shown interesting characteristics as enantioselective packing or stationary phase material in separative methods.