MARTIN Osvaldo Antonio
13Check_RNA: A tool to evaluate 13C chemical shifts assignments of RNA
ICAZATTI, A A; MARTIN, O A; VILLEGAS, M; SZLEIFER, I; VILA, J A
BIOINFORMATICS (OXFORD, ENGLAND)
OXFORD UNIV PRESS
MotivationChemical shifts (CS) are an important source of structural information of macromolecules such as RNA. In addition to the scarce availability of CS for RNA, the observed values are prone to errors due to a wrong re-calibration or miss assignments. Different groups have dedicated their efforts to correct CS systematic errors on RNA. Despite this, there are not automated and freely available algorithms for correct assignments of RNA 13C CS before their deposition to the BMRB or re-reference already deposited CS with systematic errors.ResultsBased on an existent method we have implemented an open source python module to correct 13C CS (from here on 13Cexp) systematic errors of RNAs and then return the results in 3 formats including the nmrstar one.