INVESTIGADORES
MARTIN Osvaldo Antonio
artículos
Título:
Azahar: A PyMOL plugin for construction, visualization and analysis of glycan molecules
Autor/es:
ARROYUELO, AGUSTINA.; VILA, JORGE A.; MART├ŹN OSVALDO A.
Revista:
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
Editorial:
SPRINGER
Referencias:
Lugar: Berlin; Año: 2016
ISSN:
0920-654X
Resumen:
Glycans are key molecules in many phys-iological and pathological processes. As with othermolecules, like proteins, visualization of the 3Dstructures of glycans add valuable information forunderstanding their biological function. Hence, herewe introduce Azahar, an environment for the creation,visualization and analysis of glycan molecules. Azaharis implemented in Python and works as a pluginfor the well known PyMOL package [1]. Besides thealready available visualization and analysis optionsprovided by PyMOL, Azahar includes 3 cartoon-likerepresentations and tools for 3D structure carac-terization such as a comformational search using aMonte Carlo with minimization routine and also toolsto analyse single glycans or trajectories/ensemblesincluding radius of gyration, Ramachandran plots andhydrogen bonds. Azahar is freely available to installathttp://www.pymolwiki.org/index.php/Azaharandthesourcecodeisavailableathttps://github.com/agustinaarroyuelo/Azahar