Assembly of chitosan support matrix with gallic acid-functionalized nanoparticles

LAMARRA JAVIER; GIANUZZI LEDA; RIVERO SANDRA; PINOTTI ADRIANA

MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2017 vol. 79 p. 848 - 859

0928-4931

The incorporation of gallic acid (GA) in a direct way or into nanoparticles included in chitosan edible films appears as asuitable approach to increase its preservation upon adverse conditions. The addition of nanoparticles to chitosanbasedmatrices resulted in improvements in their solubility, swelling, and mechanical properties. It is worth noting thatby means of the nanoencapsulation, the release process can be modulated in relation to the delivery of GA includeddirectly in the matrix, releasing the agent at a lower rate for a longer time. Films containing functionalized nanoparticlesare promising as a means to develop tailor-made support matrices for improving the shelf stability of the includedactive compound. From the point of view of the antimicrobial activity, all studied films showed bacteriostatic activityagainst Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Salmonella spp. and Candida vinaria.The results suggested that active films with nanoparticles could be a potential candidate for the support and controlledrelease of active compounds such as gallic acid.