Avoiding Over-Reliance on Multi-Domain Interventions for Dementia Prevention

DALY, TIMOTHY; MASTROLEO, IGNACIO; MIGLIACCIO, RAFFAELLA

JOURNAL OF ALZHEIMER'S DISEASE

IOS PRESS

Año: 2022 p. 1 - 4

1387-2877

Given the unknown therapeutic value of targeting Alzheimer´s disease pathology and the discovery of robust risk factors for dementia, non-pharmacological risk reduction (RR) is increasingly offered as an alternative to targeting Alzheimer´s disease pathology. While RR will surely be a useful tool to make public health gains, we propose solutions to three possible issues with over-reliance on multi-domain interventions to achieve RR: limited individual impact, an exclusive focus on later life, and overlooking social determinants of dementia. We argue in favor of a broader debate within the research community and greater society about how different therapeutic avenues should be explored.