INVESTIGADORES
MASTAGLIA Silvina Rosana
congresos y reuniones científicas
Título:
. Total, android and gynoid mass in normal weight and overweight women. The influence of menopause.
Autor/es:
MASTAGLIA SR; SOLIS F; BAGUR A; MAUTALEN C; OLIVERI B
Lugar:
Toronto ( Canada)
Reunión:
Congreso; 32nd Annual Meeting of The American Society for Bone and Mineral Research (ASBMR); 2010
Institución organizadora:
The American Society for Bone and Mineral Research (ASBMR)
Resumen:
Obesity is a world public health problem. It is an independent risk factor for cardiovascular disease and increases morbimortality. Dual X-ray absorptiometry is a valid method to estimate body composition. Objective: 1-to study a population of women aged 20 to 69 years to obtain normal values for total (TF), android (AF), and gynoid (GF) fat, and android/gynoid coefficient (A/G); 2- to evaluate whether menopause (MP) affects TF, AF, and GF distribution similarly in normal weight and overweight women. Material and Methods: Seventy and seven women, average age (X ±DS) 49±14 years (range 20-70 years), were studied. Those receiving hormonal contraceptives, hormone replacement therapy, or medication affecting adipose tissue, or participating in weight loss programs were excluded. Total (TF) and regional (gynoid (GF)/android (AF)) fat were determined using a GE Lunar- Prodigy machine (software Encore version 8.1). Statistical analysis was used to compare pre vs. postmenopause, dividing the population according to BMI. Results: 33 pre-MP (BMI 21±2 Kg/m2) and 44 post-MP (BMI 22±2 Kg/m2) women were normal weight (control group); 13 pre-MP (BMI 26±1 Kg/m2) and 19 post-MP (BMI 27±1Kg/m2) women were overweight. Results are shown in Table 1 (X±DS). During menopause, normal weight women showed changes in TF distribution (18.3±5 vs. 19.6±3 kg, ns) at the expense of AF (1.3±0.5 vs. 1.5±0.5kg, p<0,04) and increase in A/G index (0.7 vs. 0.8, p<0.01). Results showed no significant changes in GF. During menopause, overweight women no exhibited significant changes (GT: 27.6±3 vs. 27.0±4 kg; ns; GA: 2.2±0.5 vs. 2.3±0.5kg; ns, GG: 5.5±0.8kg vs. 5.0±0.8; ns; and A/G:0.9vs.0.9;ns).
Conclusion: 1- Fat redistribution during menopause in normal weight women involves greater android fat deposits. 2- Android and gynoid fat deposits increase equally in overweight women. 3- Peripheral conversion to estrogens may contribute to lessening changes in fat compartments in overweight women.
Table 1: Results of the studied population (X±DS)
Normal Women
Characteristics
TF
AF
GF
A/G
n
Age
BMI
Kg
%
Kg
%
Kg
%
Pre-MP
33
34±9
21±2
18.3±5
31.9±7
1,3±0,5
33.3±9
4.2±0.9
43.4±5
0.7
Post-MP
44
59±9
22±2
19.6±3
34.1±4
1,5±0,5
37.2±8
4.0±0.7
44.1±4
0.8
p
0.00
ns
ns
ns
0.04
ns
ns
ns
0.01