Prevalence and best skeletal areas to diagnose osteoporosis in women in Buenos Aires (Argentina)

MAUTALEN C ; SCHIANCHI A; SIGAL D; GIANETTI G; VIDAN V; BAGUR A ; GONZÁLEZ D ; MASTAGLIA S ; OLIVERI B

Seattle,

Congreso; ASBMR Annual Meeting; 2015

The aim of the study was to report values for osteoporosis (OP)prevalence in Buenos Aires, measuring the bone mineral density (BMD) at three different skeletal sites. From November 2012 to July 2014 a free measurement of the BMD for osteoporosis detection was offered in newspapers for women over 50 y.o. After signing an informed consent, 5448 Caucasian women living in Buenos Aires and surrounding districts were studied. BMD of the lumbar spine L1-L4 (LS), femoral neck (FN) and total femur (TH) was measured (Lunar Prodigy, software Version 12.3).Osteoporosis was defined as a T-Score ≤ -2.5.General prevalence of OP: 1021 women out of 5448 measured (18.7%), had OP at the LS or FN. Recalculating the age of the sample to that of the general population a moderate increment of the prevalence (+0.5%) was observed. Table 1 shows the OP prevalence on each area and its combination per decades of age.Up to 70 y.o a low prevalence was observed if only the FN is used. On the contrary the high prevalence up to the 70 y.o at the LS tended to land over that age. The OP prevalence at LS or FN was similar to the results of the recent NHANES report (1). The TH only add a small (0.8 %) and not significant increment. Burden of OP: 346.500 of a total population of 1.853.000 women over 50 y.o in the area had OP, at LS or FN. Only 163.500 had OP at the upper femur (FN or TH). Thus, 53% of the women would have been underdiagnosed.Conclusions: The OP prevalence on the most populated urban area of Argentina have been assessed. The results are similar to those reported on Caucasian population of US and Canada. Since measurement of only the BMD of FN overlooks the diagnosis on half of the women, it is suggested that future studies should include the measurement of the LS in combination with FN for a more accurate estimation.(1) Wright N et al, J Bone Min Res (2014)Table 1.Osteoporosis prevalence by 10 years age band and 50 y.o and over at the lumbat spine (LS) femur neck (FN) and (LS or FN)Age (y)LSFN(LS or FN)50-596.81.17.060-6917.05.518.670-7922.711.527.480 +21.428.644.650 +16.06.718.7Key Words: Osteoporosis prevalence Femoral Neck Lumbar spine Total hip