INVESTIGADORES
GILI Juan Antonio
convenios, asesorías y/o servicios tecnológicos
Título:
TESTING FOR LINKAGE DISEQUILIBRIUM: NAT2 GENE VARIANTS IN 40 ARGENTINE FAMILIES FROM 7 ECLAMC HOSPITALS
Autor/es:
SANTOS, R; LÓPEZ-CAMELO, JS; ORIOLI, I; DR. N.O. BIANCHI; BAILLIET, G; GILI, JA
Fecha inicio:
2008-06-01
Fecha finalización:
2008-06-01
Naturaleza de la
Producción Tecnológica:
metodologica-estadistica
Campo de Aplicación:
Prom.Gral.del Conoc.-Cs.Medicas
Descripción:
Human N-acetyltransferase genes encode enzimes that metabolize hydrazines and arylamines from the environement and diet. Functional NATs are present before birth, which suggests that biotransformation of aromatic amines in the mother and the fetus can contribute to the potencial fetal toxicity of aromatic amines. Furthermore, acetylation of endogenous substrates is required in order to reach normal embryonic development.
