BIOLOGICAL EFFECT OF RESPIRABLE DUST EMITTED FROM UNPAVED RURAL ROADS OF ARGENTINA ON LUNG AND SKIN CELLS

ULCHAK TATIANA1 , ASTORT FRANCISCO1 , FENOY IGNACIO1 ; PALAVECINO IMANOL 1 ; RAMIREZ HABERKON NANCY B. 2 , MENDEZ MARIANO 2 , RANDI ANDREA 3 , PANEBIANCO JUAN E. 2 , GOLDMAN ALEJANDRA1 , ORONA NADIA S.; ASTORT F

Congreso; Reunión anual de sociedades de biociencia; 2022

Rural PM comes mainly from soil erosion caused by wind and agricultural activity. Its composition varies according to the type of soil and its use, and pesticides andfertilizers can be found. In recent years, several air quality monitoring studies have found agrochemicals in air PM from rural and urban areas remote from theapplication site. Although several studies related the exposure to urban PM with the onset or exacerbation of allergies such as asthma and atopic dermatitis, thereare few studies that link rural PM with the development of these allergic disorders.Recently, epidemiological studies conducted in agricultural areas suggest a link between exposure to agrochemicals and developed to allergic diseases. However,an approach that considers the joint effect of multiple classes of environmental agents like rural PM in the development of this disease is necessary.Evaluate the effect of soil generated-PM10 from an intensive cultivation areawhere the use of agrochemicals prevails (Rural PM) from the central Pampasregion on pulmonary (A549) and skin (HaCaT) cells line