Bone mineral density and proximal femur 3D-DXA analysis in type I diabetes. Preliminary study.

BRANCE ML; RISTA L; ROJAS V; DIAZ BACLINI P; BRUN LR

Congreso; WCO-IOF-ESCEO 2021.; 2021

Type 1 DM (T1DM) is associated with low BMD and increase fracture risk related to poor diabetic control or coexistent diabetic complications. BMD by DXA may be considered an inadequate predictor of fracture risk in DM. Using pQCT and HRpQCT, a detrimental in the cortical compartment have been demonstrated in T1DM. Aim: to evaluate BMD and cortical and trabecular compartment by proximal femur 3D-DXA analysis in T1DM. Patient: Adults T1DM men and premenopausal women (n=27) and healthy subjects (n=27) as control group (CG) matched by age, sex and BMI. BMD (g/cm2) was measured by DXA (Hologic) on lumbar spine (LS), right femoral neck (FN) and total hip (TH). The 3D analysis was performed with 3D-Shaper software (v2.9, Galgo Medical, Spain): cortical BMD (sDens - mg/cm2) and trabecular volumetric BMD (trab vBMD - mg/cm3). Data were expressed as mean±SD and p