Antibody profiles induced by T. cruzi in chagasic patients with previous or current exposure to mycobacteria

PEVERENGO L; PROCHETTO E; RODELES L; VALENZUELA I; MARCIPAR I; BOTTASSO O; VICCO M

Pathogens and Disease

Oxford University Press

Lugar: Baltimore; Año: 2016 vol. 74 p. 1 - 5

Since the immune response mounted by the host to a particular microorganism might be influenced by the acquired immunological experience due to previous contact with other microorganism,we performed a cross-sectional study to explore the pattern of T. cruzi-infection related antibodies in T. cruzi-seropositive individuals presenting concomitant tuberculosis, or the antecedent of BCG vaccination Sampled individuals were grouped as follows: patients with Chagas disease, not vaccinated with BCG, who further developed pulmonary tuberculosis; individuals with Chagas disease BCG-vaccinated; and subjects with Chagas disease, presenting neither BCG scar nor tuberculosis disease. Vaccinated individuals or without tuberculosis, presented the highest values of anti-PH (p