Does the oil intake modify the risk of salivary, mammary and prostate tumors?

DEFAGÓ MD; PEROVIC NR; RUPÉREZ C; ACTIS AB

Washington

Congreso; Food, nutrition, physical activity, and the prevention of Cancer Launch Conference.; 2007

It has been estimated that a high percentage of cancer cases is related to diet since some nutrients ?like oil fatty acids- may act as promoters or protectors in the tumorigenesis process. The purpose was to analyze the relationship between the oil intake and the risk of developing salivary, mammary and prostate tumors in Córdoba, Argentina. 177 subjects of both sexes and aged 18-79 years-old, 57 cases (mammary, prostate and salivary tumors) and 120 controls, that attended two hospitals in Córdoba, Argentina, in 2005-2006 participated in this case-control study. A clinical history, a non-nutritional factor questionnaire and a validated quali-quantitative food frequency questionnaire were used to collect the data. The non-parametric Wilcoxon test was applied to compare the oil intake between cases and controls. In addition, the odds ratio (OR) was calculated and adjusted (aOR) by sex, total energy intake and toxic habits (alcohol and tobacco) with a 95% confidence interval (CI). Significant differences were observed in the salivary group regarding the consumption of sunflower oil, being higher in case (21.19 g/day) than in control subjects (9.95 g/day) (p=0.0186). On the contrary, the olive oil intake was higher in control (4.56 g/day) than in case subjects (0.48 g/day) (p=0.0082). No significant differences with respect of oil intake were found in mammary and prostate groups. A strong inverse association was found between the olive oil intake (high versus low) and risk of developing salivary tumors (aOR: 0.04; CI 95% 3.2E-03-0.41; p=0.0006). No association was observed between oil intake and the risk of mammary and prostate tumors. These preliminary results suggest that a diet including olive oil -rich in 18:1 omega-9 monounsaturated oleic fatty acid- reduces the risk of salivary tumors. Se adjunta el resumen con autores, lugares de trabajo, etc., debido a la imposibilidad de adjuntar el póster por exceder el tamaño máximo del archivo (27 MB, aún comprimido)