INVESTIGADORES
VARELA Oscar Jose
artículos
Título:
Photooxidation of thiosaccharides mediated by sensitizers in aerobic and environmentally friendly conditions
Autor/es:
TRAVERSSI, MIQUEAS G.; PEÑÉÑORY, ALICIA B.; VARELA, OSCAR; COLOMER, JUAN P.
Revista:
RSC Advances
Editorial:
Royal Society of Chemistry
Referencias:
Año: 2021 vol. 11 p. 9262 - 9273
Resumen:
A series of β-d-glucopyranosyl derivates have been synthesized and evaluated in photooxidation reactions promoted by visible light and mediated by organic dyes under aerobic conditions. Among the different photocatalysts employed, tetra-O-acetyl riboflavin afforded chemoselectively the respective sulfoxides, without over-oxidation to sulfones, in good to excellent yields and short reaction times. This new methodology for the preparation of synthetically useful glycosyl sulfoxides constitutes a catalytic, efficient, economical, and environmentally friendly oxidation process not reported so far for carbohydrates.
