INVESTIGADORES
SORDELLI Daniel Oscar
artículos
Título:
Host response to a dam mutant of Salmonella enterica serovar enteritidis with a temperature-sensitive phenotype.
Autor/es:
GIACOMODONATO M; SARNACKI SH; CACCURI RP; SORDELLI DO; CERQUETTI MC
Revista:
INFECTION AND IMMUNITY
Editorial:
ASM Press
Referencias:
Lugar: Washington DC, USA; Año: 2004 vol. 72 p. 5498 - 5501
ISSN:
0019-9567
Resumen:
The temperature-sensitive dam mutant strain of Salmonella enterica serovar Enteritidis SD1 is highly attenuated and induces innate and protective immunity in mice. SD1 activates NF-kappaB and induces gamma interferon secretion. Early interaction of the SD1 mutant with intestinal epithelial cells was associated with ruffling of enterocytes. Invading bacteria were found inside Peyer's patches after inoculation.
