The effect of a cyclooxygenase inhibitor on the in vivo polymorphonuclear leukocyte migration to Pseudomonas aeruginosa peptide chemotactins.

FONTAN PA; AMURA CR; SORDELLI DO

AGENTS AND ACTIONS

Birkhauser Verlag

Lugar: Switzerland; Año: 1993 vol. 40 p. 106 - 109

0065-4299

Pseudomonas aeruginosa chemotactic peptides (PAPCs) induced migration of polymorphonuclear leukocytes (PMNL) into the lungs when administered by the aerosol route. Migration of PMNL into the lungs and total protein content of lung lavage fluids in response to PAPCs aerosol challenge, and mortality from lethal challenge with P. aeruginosa were decreased by piroxicam treatment