INVESTIGADORES
RABINOVICH Gabriel Adrian
artículos
Título:
Galectins: Key Players at the Frontiers of Innate and Adaptive Immunity
Autor/es:
MARTINEZ ALLO, VERONICA; TOSCANO MARTA ALICIA; PINTO NICOLAS ALEJANDRO; RABINOVICH GABRIEL ADRIAN
Revista:
TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY
Editorial:
GAKUSHIN PUBL CO
Referencias:
Lugar: Tokyo; Año: 2018 vol. 30 p. 97 - 107
ISSN:
0915-7352
Resumen:
The proper function of the immune system entails multiple regulatory pathways aimed at modulating immunogenic and tolerogenicfunctions of immune cells. Galectins, a family of carbohydrate-binding proteins, control a variety of biological processes involvedin activation, differentiation, trafficking and survival of immune cells. In this review we summarize pioneer work and emergingfindings highlighting selected functions of galectins as regulatory checkpoints that control innate and adaptive immune cellprograms.
