Structure of rearranged genome segment 11 in two different rotavirus strains generated by a similar mechanism.

GONZALEZ, SILVIA; MATTION, NORA; BELLINZONI, RODOLFO; BURRONE, OSCAR

JOURNAL OF GENERAL VIROLOGY

The Society for General Microbiology

Año: 1989 vol. 70 p. 1329 - 1336

0022-1317

The structures of the rearranged genomic segment l 1 of two spontaneous swine rotavirus strains were determined. We found that the rearrangements involved the duplication of normal segment 11 in a head-to-tail orientation, and partial deletions in both monomers. The open reading frame for VP11, the protein encoded by normal segment ll, was maintained. We also showed that the two rearranged genes were transcribed into RNA molecules of the same length as their corresponding genomic segments