Functionalised Supports with Sugar Dendritic Ligand

M. MARTINELLI; M. CALDERON; C.I. ALVAREZ; M. M. STRUMIA

REACTIVE & FUNCTIONAL POLYMERS

Año: 2007 vol. 67 p. 1018 - 1026

1381-5148

Functionalised supports with sugar dendritic ligand were obtained from chemical modification on poly(hydroxylated 9 polybutadienic-hydroxyethyl methacrylate) [poly(PB-HEMA)] matrix. The matrix was activated with 1,4 butanediolpolybutadienic-hydroxyethyl methacrylate) [poly(PB-HEMA)] matrix. The matrix was activated with 1,4 butanediol 10 diglycidyl ether (BDGE) or epichlorohydrin (ECH). Later, a dendritic molecule was immobilised and submitted to reactdiglycidyl ether (BDGE) or epichlorohydrin (ECH). Later, a dendritic molecule was immobilised and submitted to react 11 with glucose (GLU) using a carbodiimide reagent. Then, glucose-containing supports were used as sorbents to retain Con-with glucose (GLU) using a carbodiimide reagent. Then, glucose-containing supports were used as sorbents to retain Con- 12 canavalin A (Con A).canavalin A (Con A). 13 Properties such as equilibrium volume swelling ratios (qv), extent of conversion of functional groups, amount of boundProperties such as equilibrium volume swelling ratios (qv), extent of conversion of functional groups, amount of bound 14 dendritic molecule and amount of coupled glucose were analysed.dendritic molecule and amount of coupled glucose were analysed.