INVESTIGADORES
LABOMBARDA Maria Florencia
congresos y reuniones científicas
Título:
Give Progesterone a chance
Autor/es:
LABOMBARDA, F
Lugar:
Puerto Alegre
Reunión:
Encuentro; Profesor invitado a la Universidad de Medicina de Puerto Alegre:; 2013
Resumen:
There is currently no standard pharmacological treatment for spinal cord
injury. Here, we suggest that progesterone, a steroid hormone, may be a
promising therapeutical candidate as it is already for traumatic brain
injury, where it has reached phase II clinical trials. We rely on
previous works showing anti-inflammatory, neuroprotective and
promyelinating roles for progesterone after spinal cord injury and in
our recent paper, in which we demonstrate that progesterone diminishes
lesion, preserves white matter integrity and improves locomotor recovery
in a clinically relevant model of spinal cord lesion.