INQUISUR 21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Towards the development of site-switchable DNA-binding peptides with built-in functionality for late-stage dimerization by 1,3-dipolar cycloaddition
Autor/es:
CURRAN III, D.P., DODERO V. I., KNOERZER T. A., MASCAREÑAS J. L.
Lugar:
New Orleans, EEUU
Reunión:
Congreso; 235th ACS National Meeting & Exposition; 2008
Institución organizadora:
American Chemical Society
Resumen:
Herein, we report the development of site-switchable DNA-binding peptides which have been modified with alkyne or azide containing amino acids at the C-terminus of the mini-protein. The alkyne or azide groups can be exploited in a late-stage 1,3-dipolar cycloaddition reaction as the critical step leading to artificial dimerization.
