INQUISUR 21779
INSTITUTO DE QUIMICA DEL SUR
Unidad Ejecutora - UE
artículos
Título:
Heck, Sonogashira, and Hiyama Reactions Catalyzed by Palladium Nanoparticles Stabilized by Tris-Imidazolium Salt
Autor/es:
MARC PLANELLAS; YANINA MOGLIE; FRANCISCO ALONSO; MIGUEL YUS; ROSER PLEIXATS; ALEXANDR SHAFIR
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Lugar: Weinheim; Año: 2014 p. 3001 - 3008
ISSN:
1434-193X
Resumen:
Palladium nanoparticles, prepared by the hydrogenation of Pd(dba)2 in the presence of a tris-imidazolium iodide as stabilizer,act an as an efficient catalyst for Heck and copperfree Sonogashira reactions with a range of aryl iodides and bromides at 0.2 mol-% Pd loading. Moreover, we describe a convenient protocol for the fluoride-free Hiyama coupling of 11 vinylsilanes with aryl iodides that involves the use of sodium hydroxide as promoter in a methanol/water mixture. Under the developed conditions, one-pot, double Heck and Hiyama?Heck reactions are successfully achieved.
